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PharmaGABA


PharmaGABA is a “farmed” form of GABA (gamma-aminobutyric acid). In all reality that’s not what “pharma” actually means, but it is a good way to think about what Pharma GABA actually is, as it is naturally derived form (e.g., not lab synthesized), through a fermentation process.

Our bodies naturally produce the amino acid GABA and it acts as a very important neurotransmitter in our central nervous system. PharmaGABA is a natural, safe and responsible method of synthesizing this compound outside the human body. This molecule is vastly important to the way we live our lives and has multiple health benefits.

Let’s take a look at what exactly PharmaGABA is, how it impacts your health and what you need to know about its stress support qualities.



Non-habit forming
Natural active ingredients
Manufactured in USA
Caffeine Free
Non-drowsy
Melatonin Free

NSF certification helps consumers identify products that have been indepnedently tested and certified to meet rigorous standards for quality, safety, and label claims.

What is PharmaGABA?


PharmaGABA is a natural form of the amino acid gamma-aminobutyric acid (GABA) that acts as a neurotransmitter in our central nervous system. This neurotransmitter is found in great abundance throughout the brain and is one of the key elements of our ability to function every day. GABA is synthesized naturally by our bodies through pathways that utilize glucose as a precursor to this abundant neurotransmitter. It is the neurotransmitter, often referred to as the “brakes of the nervous system” due to its effects of calming the nervous system, especially in times of stress.

GABA is one of the most important neurotransmitters that we synthesize and use daily. PharmaGABA is a unique form of this neurotransmitter that is synthesized outside our bodies but is derived naturally and is considered vegetarian, and safe for human consumption.

The process to produce PharmGABA is an amazing process that utilizes special bacteria that create GABA through the fermentation process. These are called Lactobacillus bacteria and they are common bacteria found in many food processes that utilize fermentation. Wines, fermented veggies like kimchi, and many other fermented foods actually utilize this same, natural bacteria.

The method for producing this specific amino acid-derived neurotransmitter is that it is given a similar “diet” of ingredients that the body uses to naturally synthesize GABA. Glucose and glutamic acid are fed to the bacteria to simulate what is called the GABA shunt, our body’s natural pathway for creating GABA.  

How Does PharmaGABA Provide Stress Support?


What Else Can PharmaGABA Be Used For?


The central nervous system is far from simple. It’s a complex, finely tuned system that is responsible for everything from learning how to walk, talk, and eat, all the way to learning how to earn a diploma. This amazing system of organic wiring is how we not only interact with the world around us, but how we adapt and find our place in it.

Our brains are the center of control for what goes on in our bodies. Even though there are reflexes that are localized to your spinal cord and nerves — the second part of the central nervous system — almost all reactions and responses flow from some kind of interaction with the brain. One aspect of how our brains respond to our bodies or produce our reality is through the use of specialized molecules called neurotransmitters.

These specialized molecules are unique to our neurons and synapses and are considered the main method of communication for our nervous system. They help transmit messages between neurons in our central nervous system and between our neurons and muscles throughout the body. They help us do everything from grow, to sleep, wake, run, walk and even feel happy or sad. 

GABA is one part of two systems in our central nervous system that affects our “up” and “down” moods and states. Those systems are glutamate receptors and GABA receptors. These unique pathways respond to their respective neurotransmitters to cause us to either feel energized and alert — glutamate — or promote more calm, and soothing effects — i.e. GABA receptors.

In fact, it has even been thought that if GABA levels get too low, it is hard for the body to relax. Because GABA can be synthesized outside the human body in the form of pharmagaba, this makes taking it as a supplement to support soothing, calming relaxation is a powerful tool in your health journey. This provides stress support with easing the mind and can even be beneficial for sleep. 

What Else Can PharmaGABA Be Used For?


While it is possible to eat foods that promote the pathways that aid in your body's natural ability to form GABA, pharmagaba is not typically used outside of its supplementary purposes. It can be found as an added supplement in protein sources or combined with other naturally occurring substances such as adaptogens.

R3SET uses a blend of all-natural substances like PharmaGABA, valerian root, L-theanine, vitamin D3, and others to produce our Calm capsule, which helps to promote comfort and focus, during a busy day. This is just one example of how PharmaGABA can be used as a powerful supplemental tool on your health journey.

Average Dosing and Side Effects


You should always consult with your primary care provider before taking pharmagaba. There have been very few reported dangers of taking pharmagaba.

Despite GABAergic drugs having a reportedly high level of side effects and addictive qualities, no such dangers have been noted with pharmaGABA, making it a generally regarded as safe (GRAS) supplement. The daily recommended dosing is 100 to 200 mg doses up to three times a day.


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