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Your stress will become your superpower

Change your Mindset, discover how to manage it, and balance your 3 body systems.


Balance the three body systems that manage stress

Balance your body’s stress systems

Let us not forget the body’s physical response to stress. Raised heart rates, wooziness, sweating, or feeling cold — sound familiar? They’re very real symptoms and they’re very addressable. That’s where we come in — R3SET Calm and Unwind.


Discover the stress management exercises that work for you

Stress Exercises: Have you tried petting a puppy?

Once you understand the way stress affects you in a situation, you have a limitless supply of actions you can take to lead it down a positive path. Learn about more stress-releasing exercises by joining the 14 Day R3SET e-mail program.


Shift your mindset to use stress as a motivating force.

So…stress is good?

Reframing your mindset about stress, going positive instead of negative, is the first step. Think of stress like pain, while it’s quite unpleasant, it has an important function, it alerts you of a problem and protects you.

The Three Body Systems and Stress

Let’s nerd out on some science for a second. The physical effects of stress can affect the 3 main body systems: the (1) nervous, (2) endocrine, and (3) immune system. When you feel stressed, these three systems that normally work in harmony fall out of sync because when one is affected, the other two are as well, and it brings on the physical symptoms.


Nervous system

Gets unbalance that’s why you start feeling on edge.



Generates hormones like cortisol - which is why your heart rate and blood pressure increases.


Immune system

Produces various chemicals that lead to inflammation, and a lowering of immune defenses. Therefore less capable to fight which is why you are more susceptible to getting sick.

Meet Our Stress Experts

Wondering who R3SET is? We’re people just like you and to be frank… Stress was stressing us too.
We’re a group of doctors, psychologists, brand builders, health experts, and flat-out wellness nerds who heard their children talking about stress and knew that they had to do something about it.

Dr. Eric First, MD, FAIS

MD - Boston U. Medical School

AD  - Food Science/Nutrition

Co-Founder/Chief Scientifc Officer, R3SET

Former Chief Scientific Officer, Alcresta Therapeutics

25+ years of scientific/medical  product dev., start-ups, innovation: Allergan, Bayer, Ipsen, Sirtex Medical, and Alcresta Therapeutics. Over 175 Records of invention, 50+ patents, numerous publications.

Research; Neuropharmacology, Neurology and Psychiatry at Boston University & Harvard Medical Schools

Click here for more Bio Info

Amelia Aldao, Ph.D.

Ph.D. - Yale University

Founder, Together CBT Cognitive Behavioral Therapy

Attending Psychologist, Mount Sinai Hospital

Visiting Scholar, Columbia University

Advisor to mental health startups and teaches cognitive behavioral therapy (CBT) at Columbia University, Mount Sinai Hospital, and Yeshiva University 

Specialty areas: cognitive behavioral therapy for anxiety, panic, OCD, stress, ADHD, sleep, depression, and related conditions

Click here for more Bio Info

Michelle Barrett, Ph.D.

Ph.D. - Clinical Psychology,  Alliant U.

Former Associate Professor and Chair for Psychology, College of Saint Elizabeth

Certified Yoga Instructor

LIcensed Psychologist, with expertise in mindfulness, behavioral techniques to manage stress (e.g., breathing and other relaxation techniques and expert  in educating and counseling adolescents

Click here for more Bio Info

Guido Schmitz

37+ yrs Bayer Consumer Health

Founder of InnCreReal, LLC 

Gen. Manager at PAPACKS US

Adjunct Professor Rutgers U.

Over 40  years exp. in consumer healthcare; packaging & manufacturing process technology innovation

Internationally recognized expert in sustainable, circular economy packaging, and process technologies.

Click here for more Bio Info

Dr. Amit Gupta, MD

Amit Gupta, MD

MD - Boston U. Medical School

Residnecy - Harvard Medical & Wash. U. Medical Center

Certified Ayurvedic Practitioner

Former Pres / Chief Strategy/Products Officer, HealthHelp, 

25+ years experience in healthcare tech, product dev. clinical/scientific. Launched/ecited several successful start-ups. 

12+ years in Ayurvedic health and yoga therapeutics; India, Turkey, Mexico & US.

Click here for more Bio Info

Matthew Roberts, PhD

25+ Yrs in Consumer Health

BS -Purdue University

PhD - Cornell, 

Executive MBA – Wash U. 

Over 25 years in driving corporate growth through science, technology, and innovation. Previously worked at Nestle as well as Abbott Nutrition.

Click here for more Bio Info

Dr Jit Maheshvari

PhD in Organic Chemistry

15 years in pharmaceutical field

22 years in the nutraceutical field

Founder of Orgenetics, pioneering plant based Organic vitamins and minerals


About our Founders & Vision for R3SET

January 2 2019-


The beginning

R3SET was founded by three former Bayer HealthCare executives who were all wrestling with stress and wanted to create a business that had real purpose in helping others.

We started R3SET with the ambition of making “stress less stressful.”

We aim to provide simple yet powerful solutions to help people better manage stress.

We envision a world where people stress less and stress better :)

April 14 2021-



Consumers continue to love R3SET!

We hear every day from moms, dads, health care workers, athletes, and even celebrities like Meghan Trainor, Gigi Gorgeous, and Paris Hilton (who decided to invest in R3SET and is our Chief Inspiration Officer).

Don’t believe us, check out our reviews on our website, Target and Amazon!,

Retailers love R3SET too!
Target expanded store availability for R3SET three times in 2019-2021 for our first two products, Calm and Unwind.
In April 2022, Target accepted our New R3SET Stress Eating product that became one of the top 10 new product launches in Target!

April 14 2022-



For 2023, Target again accepted yet another new product, R3SET Stressed Gut - an exciting new breakthrough 2023 product for those who feel stress in their stomach such as heartburn, indigestion, abdominal pain, and bloating.

Along with our esteemed Scientific Advisory Board, we have also developed:
A “Stress-Less” 14 day email program; simple tasks to help manage your stress

A 14-day online stress resiliency course; results were presented at an International Psychology Conference in 2021

A Gratitude Journal, known to be highly effective in helping manage stress.

We are well on our way to our dream of a world where people are stressing less and stressing better.

Join us on our journey!

Great for stress. Great for you, too.

Non-habit forming
Botanical ingredients
Manufactured in USA

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